2122 Actin and actin-binding proteins in proliferative vitreoretinopathy

2122 Actin and actin-binding proteins in proliferative vitreoretinopathy

TITLE: HUMAN FIBROBLASTS PRODUCE AN OPTIMAL PVR EXPERIMENTAL MODEL. AUTHORS: GRACIA-MARTIN M.C., LIBERT J. AFFILIATION: Senior research fellow, Or. Gracia-Martin M.C Prof and Head of Dep., Or. Libert J. Dep. Ophthalmology St. Pierre Hosp., Brussels ABSTRACT: Purpose. Complex tractional retinal detachments show a low percentage of succesful reattachment, due to the development of oroliferative v...

Endothelial Actin-Binding Proteins and Actin

Actin-binding proteins.

Actin is an essential component of the cytoskeleton and plays a crucial role in eukaryotic cells. The actin cytoskeleton functions in the generation and maintenance of cell morphology and polarity, in endocytosis and intracellular trafficking, in contractility, motility and cell division. In cells, the assembly and disassembly of actin filaments, and also their organisation into functional high...

Regulation of actin dynamics by actin-binding proteins in pollen.

A dynamic network of polymers, the actin cytoskeleton, co-ordinates numerous fundamental cellular processes. In pollen tubes, organelle movements and cytoplasmic streaming, organization of the tip zone, vesicle trafficking, and tip growth have all been linked to actin-based function. Further, during the self-incompatibility response of Papaver rhoeas, destruction of the cytoskeleton is a primar...

Actin-binding proteins sensitively mediate F-actin bundle stiffness.

Bundles of filamentous actin (F-actin) form primary structural components of a broad range of cytoskeletal processes including filopodia, sensory hair cell bristles and microvilli. Actin-binding proteins (ABPs) allow the cell to tailor the dimensions and mechanical properties of the bundles to suit specific biological functions. Therefore, it is important to obtain quantitative knowledge on the...